Upregulation of PD-L1 predicts poor prognosis and is associated with miR-191-5p dysregulation in colon adenocarcinoma
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چکیده
منابع مشابه
Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer
INTRODUCTION Gastric cancer is a fatal malignancy with a rising incidence rate. Effective methods for early diagnosis, monitoring metastasis, and prognosis are currently unavailable for gastric cancer. In this study, we examined the association of programmed death ligand-1 (PD-L1) and apurinic/apyrimidinic endonuclease 1 (APE1) expression with the prognosis of gastric cancer. METHODS The expr...
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The human insulin-like growth factor-II (IGF-II) gene transcribes four mRNAs (P1 mRNA-P4 mRNA), and P3 mRNA overexpression contributes to hepatocarcinogenesis. IGF-II-derived miR-483-5p is implicated in the development of cancers. Here, we investigated the involvement of miR-483-5p in P3 mRNA overexpression regulation and its role in hepatocellular carcinoma. Our results showed that miR-483-5p ...
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Accumulating evidence suggested that microRNA (miRNA) plays an important role in the carcinogenesis of bladder cancer. MicroRNA-138-5p (miR-138-5p) was dysregulated in human cancers including bladder cancer. However, its clinical significance remains unclear. We recruited 126 patients with bladder cancer in the study. Real-time quantitative polymerase chain reaction (RT-qPCR) was conducted for ...
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Aberrant expression of microRNAs (miRNAs) are believed to play a central role in the initiation and development of cancer. The aim of our study was to determine the clinical significance of serum miR-10b in melanoma. A total of 85 and 30 serum samples were obtained from patients with melanoma and healthy volunteers respectively. qRT-PCR was performed to evaluate the expression level of miR-10b ...
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ژورنال
عنوان ژورنال: International Journal of Immunopathology and Pharmacology
سال: 2018
ISSN: 2058-7384,2058-7384
DOI: 10.1177/2058738418790318